Strain-Related Differences in Mouse Neonatal Hypoxia-Ischemia
نویسندگان
چکیده
منابع مشابه
Mechanisms Underlying Neonatal Hypoxia Ischemia
Neonatal hypoxic ischemic encephalopathy (HIE) is a common health problem and occurs in approximately 16 in 1000 term infants every year. After the initial hypoxic ischemic insult, brain injury evolves for days and possibly even weeks. The severity of the injury depends on the gestational age and duration of the insult. The exact underlying mechanisms of neonatal HIE remain undefined and many d...
متن کاملS100B protein related neonatal hypoxia.
Biochemical markers have played an increasingly relevant role in the assessment of neonatal asphyxia. The S100B protein is particularly important in research conducted in this field. The purpose of this study was to underline the importance of the S100B protein in the assessment of term newborn infants with hypoxic-ischemic encephalopathy, as well as to relate it to other substances also involv...
متن کاملCorrection: Hypoxia-Ischemia and Therapeutic Hypothermia in the Neonatal Mouse Brain—A Longitudinal Study
Table 1, " Percentage injury at p18 and p30 " , incorrectly appears twice. Please see the corrected Table 1 here. open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
متن کاملNeonatal hypoxia-ischemia differentially upregulates MAGUKs and associated proteins in PSD-93-deficient mouse brain.
BACKGROUND AND PURPOSE Postsynaptic density (PSD)-93 and PSD-95 are the major membrane-associated guanylate kinases (MAGUKs) at excitatory synapses of the brain linking the N-methyl-d-aspartate receptor (NMDAR) with neuronal nitric oxide synthase (nNOS), which contributes to cell death after neonatal hypoxia-ischemia (HI). We investigated whether deletion of PSD-93 would dissociate the NMDAR fr...
متن کاملHypoxia-Ischemia and Therapeutic Hypothermia in the Neonatal Mouse Brain – A Longitudinal Study
Therapeutic hypothermia is standard of care for infants with hypoxic ischemic encephalopathy. Murine models of hypoxic-ischemic injury exist; however, a well-established mouse model of therapeutic hypothermia following hypoxic-ischemic injury is lacking. The goal of this study was to develop a full-term-equivalent murine model of therapeutic hypothermia after hypoxia-ischemia and examine magnet...
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ژورنال
عنوان ژورنال: Developmental Neuroscience
سال: 2018
ISSN: 0378-5866,1421-9859
DOI: 10.1159/000495880